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Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, dna repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects

Brain 147, 352371

Nevertheless, challenges exist, such as limited response in some patients owing to tumor heterogeneity and immune evasion mechanisms, development of resistance (primary or acquired), immune-related adverse effects (such as cytokine release syndrome), high cost and the need for sophisticated infrastructure (for a review, see 740 )

Barrett ES, Klus J, Pande A, Love T, Thurston SW, Brunner J, Kannan K, Miller RK, Groth S, O'Connor TG Environmental health : a global access science source

Silvin et al., 2022) in human specimen and translational murine models (Figure 1, Table 1)

A studied approach has included S-acetyl-glutathione paired with silybin, suggesting that combinations may be used to support liver function and oxidative balance under veterinary direction (Martello, 2023)