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Potential TREM-1 related diagnostics and therapeutics include a) soluble TREM-1, a cleaved form of TREM-1 that is increased during sepsis and thought to be a prognostic indicator of sepsis severity, b) LP17 which is a direct competitive inhibitor to the TREM-1 receptor, and c) a decoy receptor for TREM-1 [283]

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We also aim to identify areas of current ignorance and suggest possible directions for future research based on data from multiple studies

doi: 10.1016/j.mehy.2009.10.041