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Moreover, it is not known if S-5-HT mediated the effects of L-carnitine on fatigue, as it is possible that L-carnitine could have effects unrelated to S-5-HT that could reduce fatigue and in parallel promote increased synthesis of peripheral 5-HT

This is why the American Society of Clinical Endocrinology suggests that patients stop taking these drugs even before starting a ketogenic diet [184]

As a result, excessive information overload in the brain leads to the sensation of fatigue as well as enhanced pain

Serum chemerin in obese children and adolescents before and after L-Carnitine therapy: relation to nonalcoholic fatty liver disease and other features of metabolic syndrome

studied the impact of carnitine on the nutritional parameters in patients with chronic kidney failure

A laxative effect may occur in case of overdose
