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Hakozaki T, Minwalla L, Zhuang J, et al

Body-weight scaling is not straightforward: allometric differences in metabolism between a 2 kg rodent model and a 40 kg dog mean a simple g/kg extrapolation may not translate

As an added precaution for patients with a reaction history within the previous five years, which makes them higher risk, a two-step DOC, starting with 10% of the target dose, is recommended

Carbonation Carbonated alcoholic drinks increase the rate of alcohol absorption
