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The used term chronic diabetic complications is misleading for both doctors and patients, leading to the blood glucose-focused management, while ignoring the development of TOD related to other metabolic disorders in the MDS

Much of the attention and public awareness of human immunity is focused on adaptive or learned immunity

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21,22,23 As such, these alleles could produce truncated but (partially) active ADAMTS-2 enzymes lacking either the last TSP1 domain and the PLAC (protease and lacunin) domain (P1 and P2) or the two most C-terminal TSP1 domains and the PLAC domain (P5)