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J Am Pharmaceutical Assoc (Scientific ed) 46:208209
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A similar result was previously found in An
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It has also been shown that aldo-keto reductase family 1 member B1 (AKR1B1) interacts with signal transducer and activator of transcription 3 (STAT3) to up-regulate SLC7A11, which leads to increased Cys 2 uptake in lung cancer cell lines and xenograft mouse models, and further promotes lung cancer cell resistance [80]
