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Based on the available data we propose IGF-1 as a key hormone in the pathophysiology of metabolic syndrome

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Combining AOD-9604 and 5-Amino-1MQ creates synergy through complementary metabolic pathways: AOD-9604 stimulates lipolysis via beta-3 adrenergic receptors to mobilise stored triglycerides, while 5-Amino-1MQ inhibits NNMT enzyme activity to restore NAD+ availability and mitochondrial oxidative capacity

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Li, J., Sun, W., Zhu, X., Mei, Y., Li, W., & Li, J

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