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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Costelli P., Muscaritoli M., Bossola M., Penna F., Reffo P., Bonetto A., Busquets S., Bonelli G., Lopez-Soriano F.J., Doglietto G.B., et al

For instance, circulating Tfh cells can be divided into four major subsets based on CXCR3 and CCR6 coexpression: CXCR3 + CCR6 Tfh1, CXCR3 CCR6 Tfh2, CXCR3 CCR6+ Tfh17, and CXCR3 + CCR6+ Tfh17.1 cells

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Remarkably, in vitro experiments using soluble SNAREs indicate that the binding of the M105I mutant protein to cis-SNARE complexes and the NSF-mediated dissociation of these complexes were comparable to those observed with -SNAP WT 14 , suggesting that the hyh phenotype results from the -SNAP hypomorphism and not from an altered protein function per se

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