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10.3998/ark.5550190.0008.708 53 KumarA.AgnihotriV

Supporting these findings, a recent PET (positron emission tomography) imaging study by (Kato et al., 2023) demonstrated a significant reduction in Complex I availability in the anterior cingulate cortex of ASD individuals, reinforcing the hypothesis that compromised mitochondrial respiration plays a key role in ASD pathophysiology

[PubMed: 24659506] 67

In this process, the redox pairs of transition metals (e.g., Ni, Co, Cu, Mn) on the electrode surface exchange electrons with the analyte, inducing charge transfer to the electrode [141-143]
He says it's down to funding - to get a product from animal studies to human trials and to a fully licensed medicine takes years and billions of dollars
The NIST technique measures changes in a living cell's internal redox (reduction-oxidation) potential, a chemistry concept that expresses the favorability of reactions in which molecules or atoms either gain or lose electrons