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PSC quiescence and ECM reduction in vitro The metabolic crosstalk between PDAC cells and PSC leads to the overactivation of the NF-B signaling pathway, which induces stroma remodeling and PDAC progression 27
Crit Care Med (2001) 29(3):50310.10.1097/00003246-200103000-00006 22 FisherCJJrDhainautJFOpalSMPribbleJPBalkRASlotmanGJet alRecombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome

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Neoandrographolide inhibits mature osteoclast differentiation to alleviate bone loss and treat osteoporosis
doi:10.1155/2012/190309 Slucca M, Harmon JS, Oseid EA, Bryan J, Robertson RP (2010) ATP-sensitive K + channel mediates the zinc switch-off signal for glucagon response during glucose deprivation
It originated between 4,000 and 5,000 years ago in what is now present-day eastern India, Pakistan and Burma