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A reduction in the binding affinity of Insulin-like Growth Factor 1 Long Arg3 (IGF-1 LR3) for IGFBPs might potentially influence its bioavailability

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This is of significance since although corticosteroid use has long been and remains controversial for healing of tissues (Carrico et al

[DOI] [PMC free article] [PubMed] [Google Scholar] [61].Weiss N, Heydrick S, Zhang YY, Bierl C, Cap A, Loscalzo J, Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice
