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Tumor-associated macrophages (TAMs) are found at high concentrations in the ascites of patients with OC due to the induction of monocyte differentiation into TAM by factors such as leukemia inhibitory factor and IL-6 (98)

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In the rat model of induced IVD degeneration via artificial annular tears, 60 subsequent nerve sprouting following disc degeneration highly correlated to grip strength impairment was observed, most likely mediated by axial hypersensitivity