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In all our previous murine studies we have used short cycles (1014 days) of very low subcutaneal doses (20 g/kg/day) after carefully assessing its circulating concentrations and using the minimum amount that was sufficient to adequately restore physiological values of the molecule

Male SpragueDawley (SD) rats weighing 200 20 g were obtained from the Animal Experiment Center of the Fourth Military Medical University (Xian, China) and housed in a specific pathogen-free animal facility

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Signs and Symptoms of Pernicious Anemia Symptoms may develop gradually and worsen over months or years

Studies have explored its potential involvement in nitric oxide (NO) signaling, growth factor modulation (including VEGF, FGF2, and EGF receptor pathways), and FAK-paxillin pathway activation

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