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Finally, we appraise emerging therapeutic strategies targeting iron overload and metabolic pathways, discuss their stage-dependent risks and benefits, and outline the need for biomarker-guided approaches to optimize patient selection and treatment timing

The rats were given daily injections of tesofensine plus a fixed dose of 5-HTP (31 mg/kg, i.p.) and CB (75 mg/kg, i.p.) for 15 days, following one of six protocols: vehicle (control, n = 6 for each group), 5-HTP/CB (31 and 75 mg/kg), tesofensine1 (1 mg/kg, s.c.), tesofensine2 (2 mg/kg, s.c.), tesofensine1 + 5-HTP/CB, and tesofensine2 + 5-HTP/CB

What it does is keep the energy supply running in the cells doing the repair work

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

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