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This review systematically describes the multi-target mechanisms of SIRT1 in MASLD pathogenesis through its regulation of critical factors, including peroxisome proliferator-activated receptor gamma coactivator 1-, Forkhead Box O, and nuclear factor kappa-light-chain-enhancer of activated B cells, which govern hepatocyte lipid remodeling, mitochondrial quality control, autophagyendoplasmic reticulum stress balance, and Kupffer cell/T cell polarization

Both are crucial in preventing the gradual loss of transparency of the lens [11], which is the classic symptom of cataracts

2023 Aug 10:312:116446

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Factors such as additional consultations or regular check-ins can increase the overall expense but provide an additional layer of value and support that you may need