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It has been shown that CRP can trigger the complement in infarcted human myocardium, and it can activate cell death in ischemic cells

Oct 2020;130:110714

[DOI] [PMC free article] [PubMed] [Google Scholar] 528.Lee S.S.-Y., Beales D.J., Chen F.K., Yazar S., Alonso-Caneiro D., Mackey D.A

doi:10.1097/PSY.0000000000000537

239 Treatment with MAT2A inhibitors AG-24152 and AG-270 significantly reduces SAM levels, inhibits PRMT5 activity, and causes DNA damage and mitotic defects in tumor cells

Healthcare providers should stay informed of evolving research in this area and consider how adjunctive metabolic therapies might benefit their patients struggling with obesity and metabolic syndrome