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The peptide functions as a biological signal that resets gene expression patterns toward a healthier, more youthful state

writingreview and editing, R.-A.V., M.B., P.A., E.M.R

10.1038/srep24855 78 LiuJ.QuW.KadiiskaM

MMSE, mini-mental state examination

10.1016/j.theriogenology.2014.08.004 18

Paraquat, a redox cycler that produces superoxide anion, has been reported to stimulate GPx-1 promoter activity (89), and p53 can upregulate GPx-1 transcription through its action at a classic p53-consensus binding site (177, 349)