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KD therapy could be a novel, nontoxic, cost-effective adjuvant therapy for cancer patients that exploits tumor metabolic weaknesses beyond glucose/insulin signaling

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protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in -amyloid-infused rats

This is due to a change in carbohydrate metabolism, specifically an increased production of the pro-inflammatory acetate and a decreased production of butyrate, which strengthens the intestinal barrier and has anti-inflammatory effects (162)

Metabolite profiling of Arabidopsis inoculated with Alternaria brassicicola reveals that ascorbate reduces disease severity