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However, Tat-BECN1 treatment delayed the onset of AA in the C3H/HeJ mouse model [114]

The other is that BosR remains bound to RNAP-RpoS, but ligand-bound PlzA negates BosRs transactivator effect on RNAP-RpoS

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The drug also activates C-Jun N-terminal kinase (JNK), ultimately boosting cell death ( DTX can affect many signaling pathways and molecular pathways in cancer, which are involved in survival and growth of cancer

Drug Discovery Ther (2015) 9(1):3844
