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FIGURE 2 The GF protocol produced HLCs with a mature differentiated morphology

Some patients improve gradually over months, while others remain symptomatic for years

Hyaluronic acid-based aqueous serums are the most common, as they ensure good solubility of the copper complex and optimal penetration

Topical formulations of GHK-Cu are being used for their potential to support skin regeneration, improve skin appearance, and promote scalp health

Alternatively, introducing a refeed day or temporary caloric increase can reset metabolic adaptation and restore progress

Peripheral clocks are known to have organ specificity with respect to their primary entraining signals