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Description
As a result, most good plant antioxidants are unable to achieve the desired outcome because they generally have low bioavailability and some can exert pro-oxidant effects under in vivo conditions [79,80]

2.1.1 P-gp P-gp, also known as multidrug resistance protein 1 (MDR1), is an efflux transport protein involved in the absorption, distribution, and elimination of a variety of compounds

This leads to carbohydrate synthesis during day time

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Systematic investigation of the permeability of androgen receptor PROTACs

This does not mean it could not happen
