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The research discussed here was conducted in animal and cell-culture models

In Ayurvedic medicine, botanicals like neem ( Azadirachta indica ) and haritaki ( Terminalia chebula ) were employed for their potent anti-inflammatory and astringent properties, contributing to improved bowel regularity and local symptom relief [1]
DMF induces the expression of L-2-hydroxyglutarate dehydrogenase (L2HGDH) to downregulate L-2-hydroxyglutarate (L2HG) and increase global and locus-specific DNA hydroxymethylation levels
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The body weight of adult mice was estimated at 25 g, and the intraperitoneal injection volume was 250 l

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