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This is more likely to happen if you have sensitive skin or if you do not moisturise enough and do not use sunscreen

Cacciatore, I., Cornacchia, C., Pinnen, F., Mollica, A

Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight

It is not recommended for women who are carrying and feeding

Cellular and Molecular Gastroenterology and Hepatology, 2 (3), 340-357

While increased muscle mass may be desirable in some contexts, it can complicate research focused purely on fat loss and metabolic effects
