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It also helps regulate NMDA receptors, which control neurotransmitters' activity in the brain

Reaktive Sauerstoffspezies (ROS) knnen durch die Entzndungsreaktion ebenfalls das Fortschreiten der Erkrankung beschleunigen [1]

Neuroscience (2009) 164:33143.10.1016/j.neuroscience.2009.03.080 43 BenedettiFBarbiniBBernasconiAFulgosiMCColomboCDallaspeziaSet alSerotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression

While polygenic risk scores (PRS) address part of this architecture by aggregating validated risk alleles from GWAS, the proposed workflow further considers the potential cumulative burden of variants typically deemed benign, aiming to bridge the gap between population-level risk estimation and individualized interpretation (Torkamani et al., 2018)

He has also served as the US Sections Secretary and Treasurer

doi: 10.1093/gerona/gly187, 97