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This study demonstrated that some of the beneficial effects of L-carnitine could be mediated through increased liver choline levels, possibly by an elevation of betaine, which was reduced in the liver when treated with L-carnitine

Clinical treatments for mitochondrial dysfunctions after brain injury

The pathophysiology of type 2 diabetes is further complicated by its effects on lipid and amino acid metabolism

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For example, ATO has long been used to treat APL and has been shown to stabilize the p53 (R175H) mutant and restore p53 activity