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In this context, we reported that antibodies to tumor antigens conjugated with the aminobisphosphonate zoledronic acid can kill efficiently tumor and stromal cells (176)

In addition, -arrestins are involved in the phenomenon of biased agonism, where the biased ligand preferentially activates one of several downstream signaling pathways, leading to altered cellular responses

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Notably, Grx2 is not sensitive to deactivation by electrophilic or oxidative stress

The substantial hepatic storage of vitamin B 12 can delay clinical manifestations for up to 10 years after the onset of deficiency