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3.8 Mitochondrial disfunction and mtDNA therapy Mitochondria are essential organelles that are involved in IIS response via release of ROS and mtDNA and contribute to the pathogen-associated ASCVD development [89]

Overall, these studies exemplify how rapid prototyping techniques may be used to generate patient-specific tissue constructs capable of replacing expansive cartilage surfaces

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Matarrelli, B., Vitacolonna, E., D'Angelo, M., Pavone, G., Mattei, P

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