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Description
Prevents skin damage : The skin, consisting of the epidermis, dermis, and hypodermis, acts as a protective barrier against external factors like UV ray exposure , which can lead to photoaging

Galano A, Reiter RJ

Effect of parenteral micronutrient supplementation at birth on immunity, growth, and health in preweaning dairy heifers

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Circulating LPS reflects intestinal barrier integrity and microbiota-derived inflammatory load, and TLR4, as a key pattern recognition receptor that specifically binds to LPS, plays a crucial role in initiating the inflammatory response cascade in the liver

On the other hand, TLR3 receptor activation in microglia leads to increased release of IL-1 and TNF-, which increases SERT expression in astrocytes and thus 5-HT reuptake and its degradation to the metabolite 5-HIAA, thereby reducing extracellular 5-HT levels (212216)
