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Since B12 is water-soluble, your body excretes what it doesnt use, making it generally safe, even in higher doses [*]

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Subsequent research indicated that the enhancement of MET by activating UPF1 (a versatile RNA and DNA helicase) caused phosphorylation, which, in turn, controlled the 3'-UTR length of STING, leading to a decrease in STING expression in cancer cells [123]