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It has also been shown that exposure to CM remnants causes endothelial cell apoptosis, as well as an increase in the production of plasmin activator inhibitor-1 (PAI-1), a key regulator of thrombus formation, in endothelial cells (73, 106, 107)

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Back to Journals International Medical Case Reports Journal Volume 18 Striking Oral Manifestation of Primary Herpetic Gingivostomatitis: A Case Report and Review of Human Herpesvirus Infections Authors Insyafiana A , Nur'aeny N Received 23 April 2025 Accepted for publication 5 September 2025 Published 12 September 2025 Volume 2025:18 Pages 11871193 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Thomas E Hutson Anisa Insyafiana, 1 Nanan Nuraeny 2 1 Oral Medicine Specialist Study Program, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia