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confirmation in clinical trials, albeit challenging, is warranted

Excess intracellular free Fe 2+ facilitates the reduction of oxygen, generating superoxide radicals, and causes lipid peroxides through Fenton reactions, resulting in ferroptosis finally (Liu K

Astrocytes also function as glycogen reservoirs, storing glucose and mobilizing it in response to increased neuronal activity 68
Biochimica et Biophysica Acta, 1830 , 31433153

Some patients incorporate a topical retinoid or other pigment suppressors a few times a week long-term to keep melasma at bay

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