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Efferocytosis fuels requirements of fatty acid oxidation and the electron transport chain to polarize macrophages for tissue repair

Simply, the machinery that is activated during apoptosis (caspase activation) also acts through the BCL10/MALT1/CARMA pathway to activate NF B, which is the most potent activator of HIV transcription, via the HIV LTR

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Regulatory T-cells (Tregs) are crucial in modulating this balance