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Cardiovascular System Infrequent - abnormal ECG, arrhythmia, bradycardia, cardiac arrest, extrasystoles, pallor

The accumulation of fumarate in FH-deficient human cancers has been previously linked with the activation of the transcription factor Nrf2 (refs 5, 7), which elicits an antioxidant response and prevents the elevation of ROS to toxic levels in these cells

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[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Leh H

ALT-mediated telomere maintenance has the potential to extend MSC lifespan without reactivating telomerase, potentially lowering the oncogenic risk compared to hTERT overexpression

This does not mean the peptide is not doing anything