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Lipid peroxidation results in cellular membranes with compromised integrity and the formation of diffusible cytotoxic reactive aldehydes, including 4-hydroxy-2-nonenal (4HNE) and 4-hydroxyhexenal (HHE)

doi: 10.1016/S0009-9120(02)00421-6 170 SevenAErbilYSevenRInciFGulyasarTBarutcuBet al

Cobalamin and haptocorrin in human milk and cobalamin-related variables in mother and child: a 9-mo longitudinal study

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The apparent discrepancy between studies is likely due to dosage and differences in age, region, and maturation of oligodendrocyte cells (Molina-Holgado et al., 2022)

Because of this, transdermal application can be used as an alternative method of drug administration