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B12 is crucial for maintaining healthy nerve cells, producing DNA and RNA, and forming red blood cells

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In wheat leaves, -ECS activities are strongly associated with chloroplasts (Noctor et al., 2002) and subcellular localization studies of the Arabidopsis protein have convincinglydemonstrated that the enzyme is restricted to plastids (Wachter et al., 2005)

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For example, with EoE, it is more common for children to experience vomiting while adults are more likely to present with difficulty swallowing