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Up to 40% of patients undergoing chemotherapy with multiple agents experience nerve damage.

It has been found in a mouse model that chlorogenic acid affects spontaneous locomotor activity, suggesting that chlorogenic acid or its metabolite could pass the blood-brain barrier

The animals were housed in individual pens and fed a diet comprising 6% forage and 94% concentrate for 60 days

Some of these chemical messengers are free radicals, which are highly reactive species that can either gain or loose electrons, or in proper terminology, take part in oxidation or reduction reactions

Significant brightening and dark spot fading become visible after 3-4 weeks of consistent daily use