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Non-genetic factors such as stress, emotional trauma, viral infection and neuro-related abnormalities may be complicated in the pathogenesis of depression [36]

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78 A statistical analysis that included nine randomized controlled trials, involving a total of 591 women with PCOS, also reported finding omega-3 fatty acid supplementation improved insulin sensitivity, lowered total cholesterol and triglyceride levels, and raised levels of adiponectin (a signaling peptide primarily produced by fat tissue that improves insulin sensitivity and has anti-inflammatory properties)

Smart NG, Apelqvist AA, Gu X, Harmon EB, Topper JN, MacDonald RJ, Kim SK

Trammell SA, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW,