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Within dopaminergic terminals and in synaptic clefts, excess DA is autoxidized to quinone or semi-quinone (LaVoie and Hastings, 1999) to generate large amounts of H 2 O 2 , OH - , and O 2 - (Baumann et al., 2002)

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Real-time parameters of the cellular respiration or oxidative metabolism can be measured in the hepatic cells by extracellular flux assays by measuring oxygen consumption and extracellular acidification rates, and similar studies found no significant difference between absolute ATP synthesis rates between CFS and control cells (Tomas et al