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To measure the reverse reaction rates, we mixed a pre-equilibrated mixture of RT (20 M) and GSH (10 or 5 mM) with an equal volume of PBS and followed the disappearance of RT-GSH fluorescence (Fig
As for TB-500 trials, the dosages range from 2 to 5 milligrams twice weekly
Subsequently, they successfully deposited the ferroptosis inducer RSL3 onto the surface of these NPs via - stacking interactions to obtain NPs capable of targeting ferroptosis for TNBC therapy
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