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Studies indicate that NNMT inhibition by compounds such as 5-Amino-1MQ can result in reduced fat mass and improved insulin resistance

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Reconstituted 5-Amino-1MQ should be kept at 28C, protected from light, and used within 30 days

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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts

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