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Centanni M, Duntas L, Feldt-Rasmussen U, Koehrle J, Peeters RP, Razvi S et al (2025) ETA guidelines for the use of levothyroxine sodium preparations in monotherapy to optimize the treatment of hypothyroidism

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A grayscale value threshold of 84 was determined using the Otsu algorithm to threshold across the entire study to identify mineralized tissues