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Graphical Abstract Keywords: Traumatic brain injury, Intranasal drug delivery, Mitochondrial function therapeutics, Blood brain barrier, Neuroprotection Highlights Noninvasive intranasal drugs administration bypass the BBB, and can be rapidly delivered from the nasal mucosa to the brain The intranasal delivery is an attractive route for mitochondria-targeted neuroprotective drugs administration Accurate screening of intranasal compounds based on physiochemical properties is crucial When optimizing the intranasal administration by nanocarriers, drugs protection from chemical and enzymatic degradation must be carefully applied The intranasal route offers means to pharmacologically counter TBI pathogenesis in austere combat settings

[DOI] [PubMed] [Google Scholar] 111.Dahlman-Wright K, Cavailles V, Fuqua SA, Jordan VC, Katzenellenbogen JA, Korach KS, Maggi A, Muramatsu M, Parker MG, Gustafsson J-

Epinephrine binds to 1 -adrenergic receptors on -cells triggering activation of PLC

It has been shown that the concentration of LC is 2000 times higher in the epididymis and sperm cells than in the plasma [65]

Lin L, Lu W, Dai T, et al

Typical release specifications may include HPLC assay for taurine and L-carnitine, verification of the carnitine salt form and L-carnitine equivalent, loss on drying or Karl Fischer moisture, bulk and tapped density, particle size, total plate count, yeast and mold, E