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In BV2 cells, the inflammatory factor IL-6 was upregulated after FAC exposure, in turn, DMT1 was upregulated and FPN1 was downregulated following 24 hours of IL-6 stimulation, which resulted in iron overload ( Oxidative stress and autophagy were reported to participate in microglial ferroptosis likewise
10.1038/srep18896 Sci
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Oaklander and Fields, 2009)
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