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Sharabi A, Cohen E, Sulkes J, Garty M (2003) Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route
They happen regularly, and they happen most often to people who start too high because nobody told them not to

Eligible patients will be randomly assigned to one of the two treatment arms

doi: 10.1186/1479-5876-9-81 254 MandaranoAHMayaJGiloteauxLPetersonDLMaynardMGottschalkCGet al

The critical step involves injecting water along the vial wall rather than directly onto the powder
Furthermore, many patients fail treatment and need repeated courses of steroids, re-hospitalisation, or die within 90 days
