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It is not recommended to combine it in the same routine with retinol or strong exfoliating acids unless skin tolerance is confirmed

They block key enzymes, disrupt antioxidant systems, and generate free radicals

Lopez A, Harada K, Vasilakopoulou M, Shanbhag N, Ajani JA
Deplancke B, Gaskins HR (2001) Microbial modulation of innate defense: goblet cells and the intestinal mucus layer

115 Others, such as Siah1 and TRIM8, exacerbate the condition by driving lipid accumulation and inflammation
doi: 10.3389/fendo.2025.1591677
