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82,83 Thus, to assess the cytotoxicity of the oligomeric species, the effect of A 142 at different preparations of oligomerization on the viability of d-SH-SY5Y cells was investigated via an MTT assay (Figure 6)

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For example, Roche is developing trontinemab, an adaptation of an earlier antibody that is designed to cross the blood-brain barrier more effectively by exploiting a brain ferrying system