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In particular, succinate is involved in the homeostasis of reactive oxygen species (ROS), hypoxia response [54] and plays an important dual role as a signaling molecule during inflammatory responses [55]

Biologicals 44 , 117122 (2016)

It plays a significant role in tissue remodeling, immune regulation, and cellular repair

Once in the CNS, distribution and retention shape pharmacological activity

Moreover, the impact of acute stress on mood and immune biomarkers may vary depending on the degree of hormonal reactivity 3,5 which varies significantly between individuals

These snakebites are known to cause local and systemic inflammatory responses [147]