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In in vivo studies (3941), quercetin has reduced arthritic scores and improved symptoms significantly in RA mice via inhibiting neutrophil infiltration and reducing levels of pro-inflammatory cytokines such as interferon , TNF-, monocyte chemotactic protein 1, IL-6, and IL-17

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Addionally, both AMS and AMSOhave been found to decrease induced hypertrophy in rat hearts [82]

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