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(5.7, 8.1, 8.3) Adverse Reactions/Side Effects The most common adverse reactions (incidence 20%) of ALIMTA, when administered as a single agent are fatigue, nausea, and anorexia

It also prevents hardening of the arteries and has been shown to help in the treatment of depression and anxiety

Preclinical studies document significant brain concentrations after systemic (including oral) administration, with behavioral improvements in hippocampal-dependent tasks confirming functionally relevant CNS penetration (PMID: 23055539)

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Stay Hydrated Dehydration can make withdrawal symptoms like headaches and fatigue worse

Investigation of the safety and efficacy of edaravone in 20 ALS patients who received this antioxidant intravenously indicated that this drug is safe and may delay the progression of functional motor disturbances by reducing OS (Yoshino and Kimura, 2006) (Table 1)