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With step by step studies, researchers found that ferroptosis could be regulated by a variety of ways including redox homeostasis (30), iron metabolism (31), mitochondrial activity (32), metabolism of amino acids, lipids, and glucose (33)

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Other strategies, such as targeting the RAS signaling pathway to suppress its mediated dysfunction in macrophage phagocytosis, remain at the theoretical exploration stage (165, 166)

3.6.3.2 Microbial metabolites A substantial body of research highlights the role of gut microbiota and their metabolites, particularly SCFAs, in regulating metabolic, endocrine, and immune functions, with emerging evidence pointing to their involvement in neuro-immunoendocrine pathways through the MGBA (Silva et al., 2020)

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The kind that comes without the harsh chemicals or complicated routines, and is not only affordable but also sustainable in the long run